CYSTIC FIBROSIS GENE MODIFIER STUDY

囊性纤维化基因修饰研究

• 批准号: 6114864
• 负责人: BRUCE C MARSHALL
• 金额: $ 2.81万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6114864
• 关键词: clinical research; cystic fibrosis; gene expression; genetic mapping; human population genetics; human subject; phenotype

Phenotypic expression of the pulmonary disease in cystic fibrosis (CF) is quite variable even within patients with identical mutations of the CFTR locus. The hypothesis we will utilize is that other genetic determinants modify the phenotypic expression of the disease.

肺囊性纤维化的表型表现 即使在具有相同突变的患者中， CFTR基因座。 我们将利用的假设是， 决定因素修饰疾病的表型表达。