CORRECTION OF PANCREATIC STEATORRHEA DETECTED BY NOVEL METHOD

该方案有两个主要目的：1）研究一种新的脂肪代谢试验，2）研究膳食脂肪含量对用猪胰脂肪酶治疗的慢性胰腺炎的脂肪代谢的影响。该协议由两个链接但略有不同的协议组成。在母方案（37-98-00）中，我们研究了3例患者。 由于方案的胃插管部分和在GCRC中相对较长时间停留的要求，我们选择修订方案（37-98-01）。 该协议现在只涉及收集两个72小时的粪便，而患者在家里进行特殊饮食。 不涉及GCRC停留。 方案37 -98-01中的患者招募略有增加。我们计划将合适的患者纳入母方案（37-98-00）或修订方案（37-98-01），等待患者接受。 大多数患者的趋势是在家中进行研究，而不是在Saint Marys GCRC中花费时间。到目前为止，还没有根据方案所做工作发表的出版物。

This protocol has two main objectives: 1) to study a novel test for steatorrhea and 2) to study the effect of fat content of meal on steatorrhea of chronic pancreatitis treated with porcine pancreatic lipase. This protocol consists of two linked, but slightly different protocols. In the parent protocol (37-98-00), we studied three patients. Because of the gastric intubation part of the protocol and the requirement for relatively long stays in the GCRC, we elected to amend the protocol (37-98-01). The protocol now only involves collection of two 72-hour stools while patients are on a special diet at home. There is no GCRC stay involved. Recruitment of patients is slightly increased in protocol #37-98-01. We intend to enter suitable patients into the parent protocol (37-98-00) or the amended (37-98-01) protocol pending patient acceptance. The trend for most patients is to do the study at home, rather than spending time in the Saint Marys GCRC. To date, there are no publications resulting from the work done in the protocol.