CORRECTION OF PANCREATIC STEATORRHEA DETECTED BY NOVEL METHOD

该方案有两个主要目的：1)研究一种新的脂肪漏检测方法；2)研究膳食脂肪含量对猪胰脂肪酶治疗慢性胰腺炎脂肪漏的影响。该协议由两个相连但略有不同的协议组成。在家长方案（37-98-00）中，我们研究了三名患者。由于方案中有胃插管的部分，且GCRC要求患者住院时间较长，我们选择修改方案（37-98-01）。该方案现在只涉及收集两次72小时的粪便，同时患者在家中进行特殊饮食。没有GCRC的参与。在37-98-01方案中，患者的招募略有增加。我们打算将合适的患者纳入母方案（37-98-00）或修订后的方案（37-98-01），等待患者接受。大多数患者的趋势是在家里做研究，而不是花时间在圣玛丽GCRC。迄今为止，还没有因议定书所做的工作而发表的文章。

This protocol has two main objectives: 1) to study a novel test for steatorrhea and 2) to study the effect of fat content of meal on steatorrhea of chronic pancreatitis treated with porcine pancreatic lipase. This protocol consists of two linked, but slightly different protocols. In the parent protocol (37-98-00), we studied three patients. Because of the gastric intubation part of the protocol and the requirement for relatively long stays in the GCRC, we elected to amend the protocol (37-98-01). The protocol now only involves collection of two 72-hour stools while patients are on a special diet at home. There is no GCRC stay involved. Recruitment of patients is slightly increased in protocol #37-98-01. We intend to enter suitable patients into the parent protocol (37-98-00) or the amended (37-98-01) protocol pending patient acceptance. The trend for most patients is to do the study at home, rather than spending time in the Saint Marys GCRC. To date, there are no publications resulting from the work done in the protocol.