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PULMONARY ASPERGILLOMA

PULMONARY ASPERGILLOMA
肺曲菌瘤
批准号：
6265520
负责人：
MARC A JUDSON
金额：
$1.74万
依托单位：
MEDICAL UNIVERSITY OF SOUTH CAROLINA
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6265520
关键词：
aspergillosis clinical research drug adverse effect drug screening /evaluation human subject human therapy evaluation itraconazole lung disorder microorganism disease chemotherapy

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中文摘要
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英文摘要
Main Objective- to compare the safety and efficacy of itraconazole oral solution in cyclodextrin with placebo (hydroxypropyl-B-cyclodextrin) in the treatment of pulmonary aspergilloma. Specific Objectives: 1. To evaluate the efficacy and safety of itraconazole oral solution in cyclodextrin in the treatment of patients with pulmonary aspergilloma. 2. To determine association between serum itraconazole drug levels and outcome. 3. To identify subpopulations of patients with aspergilloma that would benefit in terms of morbidity and mortality by treatment with itraconzaloe oral solution in cyclodextrin.
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