ORAL GLUCOSE TOLERANCE TEST & PREPARATORY DIET

几十年来，连续三天每天服用150克碳水化合物的预备饮食一直被用作诊断妊娠期糖尿病的口服葡萄糖耐量试验(OGTT)的标准准备。孕妇需要预备性饮食需要得到确认。避免饮食将导致糖耐量测试的更简单的管理。这项研究的目的是确定预备饮食是否会显著改变对孕妇进行的葡萄糖耐量测试的结果。孕妇通常会在怀孕24-28周期间接受1小时的血糖挑战。结果不正常的女性将组成研究组。3小时的口服葡萄糖耐量试验将在没有准备饮食的情况下进行。然后，患者将接受为期3天的标准高碳水化合物饮食。参与者将被提供含有至少150毫克碳水化合物的食物，之后将重复进行葡萄糖耐量测试。每个患者将作为她自己的对照；OGTT的结果将被比较有没有准备饮食。一项针对20名患者的初步研究将首先进行测试。根据这些结果，将计算样本量。

The administration of a preparatory diet containing 150 grams of carbohydrates/day for three days has been used for decades as a standard preparation for an oral glucose tolerance test (OGTT) for the diagnosis of gestational diabetes. The need for a preparatory diet in pregnant women needs to be confirmed. Avoiding the diet will result in simpler administration of the glucose tolerance test. The objective of this study is to determine whether a preparatory diet significantly alters the results of a glucose tolerance test administered to pregnant women. Pregnant women are routinely offered a 1-hour glucose challenge between 24-28 weeks gestation. Women with an abnormal result will compose the study group. A 3-hour oral glucose tolerance test will be administered without a preparatory diet. The patient will then be placed on a standard high carbohydrate diet for 3 days. Foods containing at least 150 mg of carbohydrate will be supplied to the participant, after which the glucose tolerance test will be repeated. Each patient will serve as her own control; the results of the OGTT with and without a preparatory diet will be compared. A pilot study of 20 patients will initially undergo testing. Based on these results, a sample size will be calculated.