EFFECTS OF FORMULA SUPPLEMENTED W/ LC PUFA ON GROWTH OF PREEMIES

补充 LC PUFA 的配方奶对早产儿生长的影响

• 批准号: 6265666
• 负责人: BRENDA H MORRIS
• 金额: $ 1.11万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6265666
• 关键词: arachidonate; clinical research; clinical trial phase I; developmental nutrition; diet therapy; dietary supplements; growth /development; human subject; human therapy evaluation; infant human (0-1 year); longitudinal human study; milk; nutrition related tag; omega 3 fatty acid; premature infant human; unsaturated fatty acids

Mead Johnson Nutritionals has developed milk-based formulas in which part of the lipid has been replaced with sources of docosahexaenoic acid (DHA) and arachidonic acid (ARA). We hypothesize that the addition of these long chain polyunsaturated fatty acids (LC PUFA) will improve the growth and development of preterm infants. This study is a 2-phase, double-blind, randomized, controlled, parallel designed, prospective trial of infant formulas containing the LC PUFA DHA and ARA. The objectives of this study are to evaluate the safety and efficacy of feeding preterm infants formula supplemented with long chain polyunsaturated fatty acids (DHA and ARA) up to one year corrected age.

美赞臣营养公司开发了以牛奶为基础的配方，其中部分脂肪已被二十二碳六烯酸(DHA)和花生四烯酸(ARA)的来源所取代。我们推测，添加这些长链多不饱和脂肪酸(LC PUFA)将改善早产儿的生长发育。这项研究是一项两阶段、双盲、随机、对照、平行设计的婴儿配方奶粉前瞻性试验，其中包含LC PUFA DHA和ARA。本研究的目的是评价添加长链多不饱和脂肪酸(DHA和ARA)的早产儿配方奶粉喂养一岁以下早产儿的安全性和有效性。