CORE--MORPHOLOGY

该核心将负责准备、切片和染色 用于常规组织学、免疫和酶组织化学的样本， 原位杂交 核心还将为中心提供培训 研究人员和他们的同事在使用切片机，显微镜， 和显微摄影。 核心将包括60%的支持， 经验丰富的SRA III在卡恩博士的监督下。 所有 各项目将广泛利用这一核心。 这一点特别 对于项目5至关重要，其中组织，而不是细胞培养物， 专用。 这必须嵌入和部分，以获得 任何形态学信息 由于项目3和4提出了广泛的 使用该模型的一些他们提出的实验，因为 项目1和2利用组织以及细胞培养，这一核心是 对所有研究者来说都是必不可少的。

This core will be responsible for preparing, sectioning and staining samples for routine histology, immuno- and enzyme histochemistry, and in situ hybridization. The core will also provide training to Center investigators and their associates in the use of microtomes, microscopes and in photomicrography. The core will consist of 60% support for a highly experienced SRA III under the supervision of Dr. Kahn. All projects will utilize this core extensively. It will be particularly essential for Project 5 in which tissue, rather than cell cultures, is used exclusively. This must be embedded and section in order to obtain any morphological information. Since Project 3 and 4 propose extensive use of the model for some of their proposed experiments, and since Projects 1 and 2 utilize tissue as well as cell cultures, this core is essential for all investigators.