STEROID HORMONES/MONOAMINE NEUROTRANSMITTERS IN PREMENSTRAL SYNDROME

月经黄体期的身体和情绪变化 月经周期（PMS）在女性中非常常见。 经前综合症的原因尚不清楚， 可能与类固醇激素和 神经递质系统 卵巢类固醇激素和单胺 已知神经递质在诊断中起重要作用。 治疗PMS。 该项目的主要目标是建立一个 卵巢类固醇激素水平与卵巢癌的发生、发展及预后之间的相关性 经前综合征患者血浆单胺类神经递质的变化 与非经前综合症健康对照组相比。 这项研究可能会导致 更好地了解PMS的病因，并希望改善 诊断和治疗策略。 定量 将对血浆中的类固醇和神经递质进行分析 气相色谱-质谱联用技术（GC/MS）。 将进行统计分析以测量显著相关性 这些组件之间。 血液样本将从 威廉姆斯医疗诊所，冬青泉，MS。两名本科生 来自Rust College的学生将有机会参加 研究项目通过实践经验。

Physical and emotional changes during the luteal phase of the menstrual cycle (PMS) are very common among women. The cause of PMS is unknown and may be related to interactions between steroid hormones and the neurotransmitter systems. The ovarian steroid hormones and the monoamine neurotransmitters are known to play a significant role in the diagnostic and treatment of PMS. The main goal of this project is to establish a correlation between the levels of the ovarian steroid hormones and the monamine neurotransmitters in the plasma of PMS patients and compare it to those of non-PMS healthy control subjects. This study may lead to better understanding the etiology of PMS and hopefully lead to improved diagnostic and treatment strategies for this syndrome. The quantitative analysis of steroids and neurotransmitters in plasma will be performed by the gas chromatography mass spectrometric technique (GC/MS). Statistical analysis will be made to measure significant correlation between these components. The blood samples will be obtained from the Williams Medical Clinic, Holly Springs, MS. Two undergraduate students from Rust College will have the opportunity to participate in this research project through hands-on experience.