DEVELOPMENTAL GRANT FOR THE ROCHESTER COHRCD

罗切斯特 COHRCD 发展补助金

• 批准号: 2397507
• 负责人: Lawrence A. Tabak
• 金额: $ 15.9万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-01 至 1999-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2397507
• 关键词: biomedical facility; congenital oral /facial /cranial defect; craniofacial; dental health education; dental research; education evaluation /planning; growth /development; oral health

The University of Rochester has identified as a high priority institutional goal the establishment of a Comprehensive Oral Health Research Center of Discovery in the field of craniofaciaI biology. Many Of the key elements of a successful COHRCD are already in place at the University of Rochester and its collaborating institutions. The University has strong programs in developmental biology, which have been enhanced via collaboration with colleagues at the University of California at Berkeley. A clinical team devoted to treatment of craniofacial anomalies is in place; it is composed of persons from Strong Memorial Hospital. Children's Hospital at Strong (the tertiary care facilities for Monroe and the surrounding 12 counties of the Finger Lakes region) and the Eastman Dental Center. Significant resources to study the epidemiology of craniofacial defects are avaIlable through a consortium with the New York State Health Department which maintains a state-wide registry of craniofacial birth defects. Regional outreach programs for the large deaf community in Rochester and surrounding counties, and other programs designed to foster and promote oral health, are run through specific units of the University. Eastman Dental Center- and the New York State Health Department. The specific aims of the Rochester COHRCD developmental grant (P20) are to: I) Develop the research and administrative support structures to ensure the success of a COHRCD; 2) Promote and facilitate the further development and coordination of research programs in craniofacial biology encompassing both basic and applied research; 3) Develop programs to encourage and facilitate activities which move fundamental and applied research findings from the bench to the bedside; 4) Develop programs to provide effective outreach to the community; and 5) Promote excellence in basic and clinical education related to craniofacial defects for health care professionals. The institutional commitment to these goals is reflected in the significant resources that have been provided by the University for this program. These include matching funds to help support pilot projects, the construction of a zebrafish core facility, and the recruitment of new faculty who will participate in this project.

罗切斯特大学已确定为高度优先 建立全面口腔健康体系的机构目标 颅面生物学领域发现研究中心。许多 成功的 COHRCD 的关键要素已经在 罗切斯特大学及其合作机构。这 大学在发育生物学方面拥有强大的课程， 通过与大学同事的合作得到加强 加州伯克利。致力于治疗的临床团队 颅面异常存在；它由来自以下国家的人员组成： 强纪念医院。斯特朗儿童医院（三级医院） 门罗及手指周边 12 个县的护理设施 湖区）和伊士曼牙科中心。重要资源 研究颅面缺陷的流行病学可通过 与纽约州卫生局组成的财团，维持 全州颅面出生缺陷登记处。区域外展 为罗切斯特及周边地区的大型聋人社区提供的计划 县以及旨在促进和促进口腔健康的其他计划， 由大学的特定单位运营。伊士曼牙科中心- 和纽约州卫生局。 罗切斯特 COHRCD 发展补助金 (P20) 的具体目标是 I) 发展研究和行政支持结构 确保 COHRCD 的成功； 2) 促进和促进进一步 颅面研究项目的开发和协调 生物学包括基础研究和应用研究； 3）开发 鼓励和促进具有根本意义的活动的计划 并将研究成果从实验室应用到临床； 4）开发 向社区提供有效外展活动的计划； 5) 推广 颅面相关基础和临床教育的卓越表现 医疗保健专业人员的缺陷。机构承诺 这些目标反映在已投入的大量资源中 由大学为此计划提供。这些包括匹配 资金帮助支持试点项目、斑马鱼的建设 核心设施，以及招募将参与的新教师 在这个项目中。

项目成果

Microtia associated with the Kabuki (Niikawa-Kuroki) syndrome.

与歌舞伎（新川黑木）综合征相关的小耳症。

• DOI: 10.1067/mhn.2001.116780
• 发表时间: 2001
• 期刊: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
• 作者: Fong,CT;Wang,M;Young,EC;Hogan,CA;Tallents,RH;Kyrkanides,S;Liptak,GS;Sanger,JA;Frisina,RD
• 通讯作者: Frisina,RD