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PAMIDRONATE ON BONE DENSITY IN PATIENTS WITH CYSTIC FIBROSIS

PAMIDRONATE ON BONE DENSITY IN PATIENTS WITH CYSTIC FIBROSIS
帕米膦酸钠对囊性纤维化患者骨密度的影响
批准号：
6244947
负责人：
ROBERT M ARIS
金额：
$1.34万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-01-06 至 1997-11-30
来源：
https://reporter.nih.gov/project-details/6244947
关键词：
bone density clinical research cystic fibrosis drug screening /evaluation human subject human therapy evaluation osteoporosis phosphonate skeletal disorder chemotherapy skeletal pharmacology

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中文摘要
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英文摘要
The hypothesis is that pamidronate, a biphosphonate drug that inhibits bone resorption, will be efficacious in reversing bone demineralization and preventing features in CF patients. We plan to test this hypothesis in a group of CF patients who have undergone or are awaiting lung transplanation because this cohort likely represent a worst-care scenario of osteoporosis and, therefore, the chances of significant benefit from therapy are high.
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Bisphosphonates on Bone Mineral Density in Patients with Cystic Fibrosis
The Effects of Alendronate on Bone Metabolism in Patients with CF
EFFECTS OF ALENDRONATE ON BONE METABOLISM IN PATIENTS WITH CYSTIC FIBROSIS
PAMIDRONATE ON BONE DENSITY IN PATIENTS WITH CYSTIC FIBROSIS
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