COMPARATIVE ANALYSIS OF THE METABOLIC RESPONSE TO ACTH STIMULATION

ACTH 刺激代谢反应的比较分析

• 批准号: 6245083
• 负责人: JUDSON J VAN-WYK
• 金额: $ 1.34万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-01-06 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6245083
• 关键词: adrenalectomy; adrenocorticotropic hormone; child (0-11); clinical research; congenital adrenal hyperplasia; endocrine disorder chemotherapy; hormone regulation /control mechanism; hormone therapy; human subject; human therapy evaluation; peptide hormone metabolism

The purpose of this study is to evaluate the metabolic response to ACTH stimulation in children with congenital adrenal hyperlasia before and after prophylactic adrenalectomy, and compare it to normal controls. One possible objection raised to adrenalectomy in these patients has been that the loss of all adrenal tissue may leave them at a greater risk for adrenal crisis in times of stress.

本研究的目的是评估ACTH的代谢反应