AMELIORATION OF HIV WASTING--EXERCISE AND MEGESTROL ACETATE

改善艾滋病毒消瘦——运动和醋酸甲地孕酮

• 批准号: 6245158
• 负责人: JAMIE H VON ROENN
• 金额: $ 1.2万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-07-15 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6245158
• 关键词: AIDS; AIDS therapy; body composition; cachexia; clinical research; exercise; human subject; human therapy evaluation; outcomes research; pregnane compound; weight loss

Involuntary weight loss or wasting indicative of severe protein energy malnutrition is a frequent complication of AIDS. Since wasting associated with AIDS is characterized by a loss of muscle mass, and because the prognosis for patients with AIDS worsens with the loss of fat free mass, we hypothesize that a program of progressive resistance and aerobic exercise prescribed in combination with megestrol acetate will result in greater increases in lean body mass than either intervention alone for patients with AIDS-related weight loss.

非自愿的体重减轻或消瘦表明严重的蛋白质能量