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VITAMIN A AND E MAY INCREASE RETINOPATHY IN PREMATURE INFANTS

VITAMIN A AND E MAY INCREASE RETINOPATHY IN PREMATURE INFANTS
维生素 A 和 E 可能会增加早产儿视网膜病变
批准号：
6245322
负责人：
Christine A Gleason
金额：
$2.23万
依托单位：
JOHNS HOPKINS UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-03-05 至 1997-11-30
来源：
https://reporter.nih.gov/project-details/6245322
关键词：
blood chemistry clinical research disease /disorder proneness /risk drug adverse effect human subject infant human (0-1 year) longitudinal human study photosensitizing agents porphyrins premature infant human retinoids retinopathy of prematurity tocopherols vitamin therapy

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中文摘要
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英文摘要
The primary objective of our clinical research study is to determine whether some premature babies are at higher risk of developing retinopathy of prematurity (ROP) because they have elevated levels of protoporphyrin IX, a photosensitizer, along with low levels of Vitamin A and E. If we could determine (at birth) which babies are at highest risk, we could develop preventative strategies targeted specifically to them. During this past study period, we discovered a previously unrecognized technical difficulty with one of the blood tests wer are performing. While we are investigating this problem and searching for alternatives, we have suspended enrollment of patients in the study.
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