5 ALPHA REDUCTASE 2 DEFICIENCY--STUDIES OF DIHYDROTESTOSTERONE IN FEMALES

5 α还原酶2缺乏症--女性二氢睾酮的研究

• 批准号: 6245131
• 负责人: JULIANNE IMPERATO
• 金额: $ 5.36万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-02-24 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6245131
• 关键词: clinical research; dihydrotestosterone; enzyme deficiency; female; hirsutism; hormone regulation /control mechanism; human subject; menstrual cycle; ovary disorder; polycystic ovary syndrome; reproductive development; testosterone 5 alpha reductase

The specific aim of the major part of this study is to characterize the role of the hormone DHT in female physiology and to test the hypothesis that DHT plays a role in normal sexual hair development, the menstrual cycle, and in the development of hirsutism, acne and polycystic ovarian disease.

本研究主要部分的具体目的是表征 DHT 激素在女性生理学中的作用并检验该假设 DHT 在正常的性毛发发育、月经中发挥作用 周期，以及多毛症、痤疮和多囊卵巢的发展 疾病。