DETERMINATION OF PROTEIN SYNTHESIS AND CATABOLISM IN NEONATES

新生儿蛋白质合成和分解代谢的测定

• 批准号: 6246090
• 负责人: PATTI THUREEN
• 金额: $ 1.71万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-03-20 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6246090
• 关键词: biotransformation; clinical research; dietary proteins; human subject; newborn human (0-6 weeks); nutrition; nutrition related tag; premature infant human; protein biosynthesis

The clinical circumstances of the preterm and sick term infant are quite complex from a metabolic and nutritional viewpoint. The calculation of protein catabolism and synthesis in infants with a wide variety of disease states could be used as a guideline to help recognize the infants who are at a particular nutritional risk and identify those who are becoming increasingly catabolic. The information gained from the quantification of protein breakdown in neonates and the examination of net protein synthesis vs. catabolism, would provide a more accurate estimate of protein requirements by neonates and potentially maximize their nutritional status.

早产儿和患病足月儿的临床情况相当 从新陈代谢和营养的角度来看，这是一种复合体。的计算方法 多种疾病婴儿的蛋白质分解代谢和合成 各州可以作为指导方针，帮助识别那些 处于特定的营养风险，并确定哪些人正在成为 越来越分解代谢。从量化过程中获得的信息 新生儿蛋白质分解及净蛋白检测 合成与分解代谢，将提供一个更准确的估计 新生儿对蛋白质的需求，并有可能使他们的 营养状况。