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NATURAL HISTORY OF ANAL NEOPLASIA--ACTG 216

NATURAL HISTORY OF ANAL NEOPLASIA--ACTG 216
肛门肿瘤的自然史--ACTG 216
批准号：
6246371
负责人：
JOEL Michael PALEFSKY
金额：
$4.89万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-02-04 至 1997-11-30
来源：
https://reporter.nih.gov/project-details/6246371
关键词：
13 cis retinoate HIV infections cancer prevention cancer risk chemoprevention clinical research combination cancer therapy dosage drug screening /evaluation gastrointestinal epithelium histopathology homosexuals human subject human therapy evaluation interferon alpha male neoplasm /cancer chemotherapy neoplasm /cancer relapse /recurrence neoplasm /cancer surgery neoplastic process preneoplastic state rectum neoplasms virus related neoplasm /cancer

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中文摘要
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英文摘要
To study the development and progression of precancerous cytologic and histopathologic changes of the anal epithelium amonth HIV-positive and negative homosexual men, to identify risk factors, perform dose escalation studies of isotretinoin and interferon-alpha, determine efficacy of prevention recurrence by 1)ablation alone, 2) ablation in combination with isotretinoin, 3) ablation in combination with isotretinoin and interferon-alpha.
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