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Discovery and Characterisation of Novel Tick Evasins as Inhibitors of Chemokine-mediated Inflammation

Discovery and Characterisation of Novel Tick Evasins as Inhibitors of Chemokine-mediated Inflammation
作为趋化因子介导的炎症抑制剂的新型蜱虫逃逸素的发现和表征
批准号：
nhmrc : 1140867
负责人：
A/Pr Martin Stone
金额：
$44.28万
依托单位：
Monash University
依托单位国家：
澳大利亚
项目类别：
Project Grants
财政年份：
2018
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2018-01-01 至 2020-12-31
来源：
https://researchdata.edu.au/discovery-characterisation-novel-mediated-inflammation/1319329
关键词：
DiscoveryCharacterisationNovelTickEvasins

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中文摘要
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英文摘要
An important aspect of inflammatory diseases is the migration of white blood cells into the affected tissues. This is controlled by a group of proteins called chemokines. Ticks, which live on mammalian hosts, produce proteins called evasins, which interact with host chemokines and thereby prevent inflammatory responses. This project will discover new tick evasins, study their chemokine interactions and investigate their ability to block inflammation in allergic asthma.
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Mechanisms of Ligand-Selective Signalling by Chemokine Receptors
  • 批准号：
    nhmrc : GNT1140874
  • 项目类别：
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  • 资助金额：
    $74.94万
  • 财政年份：
    2018
  • 负责人：
    A/Pr Martin Stone
  • 依托单位：
    Monash University
Mechanisms of Ligand-Selective Signalling by Chemokine Receptors
  • 批准号：
    nhmrc : 1140874
  • 项目类别：
    Project Grants
  • 资助金额：
    $50.67万
  • 财政年份：
    2018
  • 负责人：
    A/Pr Martin Stone
  • 依托单位：
    Monash University
Discovery and Characterisation of Novel Tick Evasins as Inhibitors of Chemokine-mediated Inflammation
  • 批准号：
    nhmrc : GNT1140867
  • 项目类别：
    Project Grants
  • 资助金额：
    $65.48万
  • 财政年份：
    2018
  • 负责人：
    A/Pr Martin Stone
  • 依托单位：
    Monash University
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