COMPARATIVE STUDY OF 3TC VS DDI VS ZDV + DDI IN CHILDREN

3TC VS DDI VS ZDV DDI 在儿童中的比较研究

• 批准号: 6113730
• 负责人: FRANK GIGLIOTTI
• 金额: $ 1.48万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6113730
• 关键词: 2'3' dideoxyinosine; AIDS therapy; HIV infections; antiAIDS agent; child (0-11); clinical research; combination chemotherapy; human immunodeficiency virus 1; human subject; human therapy evaluation; lamivudine; zidovudine

To compare the efficacy of treatment with 3TC/ZDV in combination versus the better of ddI monotherapy versus ZDV/ddI combination therapy in symptomatic HIV- 1-infected children who have received <56 days of prior antiretroviral therapy.

在既往接受抗逆转录病毒治疗<56天的有症状HIV- 1感染儿童中，比较3 TC/ZDV联合治疗与ddI单药治疗与ZDV/ddI联合治疗的疗效。