PREVALENCE AND PROGNOSTIC SIGNIFICANCE OF T WAVE ALTERNANS IN SEVERE CHF

严重 CHF 中 T 波交替的患病率和预后意义

• 批准号: 6220052
• 负责人: DANIEL BLOOMFIELD
• 金额: $ 0.04万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6220052
• 关键词: biomarker; cardiovascular disorder epidemiology; clinical research; congestive heart failure; electrocardiography; heart disorder diagnosis; human mortality; human subject; myocardial ischemia /hypoxia; myocardium disorder; prognosis

The aim of this study to evaluate the prevalence and prognostic signicance of T-wave alternans in patients with severe CHF. We hypothesize that: (1) patients with T-wave alternans (regardless of the etiology of their heart failure) will have an increased cardiac mortality compared with patients who do not have T-wave alternans, and (2) T-wave alternans will be significantly more common in patients with severe CHF from an from an ischemic cardiomyopathy than in pts. with severe CHF from a non-ischemic cardiomyopathy.

本研究的目的是评估严重CHF患者T波电交替的患病率和预后意义。 我们假设：（1）与没有T波电交替的患者相比，具有T波电交替的患者（无论其心力衰竭的病因如何）将具有增加的心源性死亡率，以及（2）T波电交替在缺血性心肌病引起的严重CHF患者中比在患者中显著更常见。 非缺血性心肌病导致严重充血性心力衰竭