PREVALENCE AND PROGNOSTIC SIGNIFICANCE OF T WAVE ALTERNANS IN SEVERE CHF

严重 CHF 中 T 波交替的患病率和预后意义

• 批准号: 6117678
• 负责人: DANIEL BLOOMFIELD
• 金额: $ 2.21万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6117678
• 关键词: biomarker; cardiovascular disorder epidemiology; clinical research; congestive heart failure; electrocardiography; heart disorder diagnosis; human mortality; human subject; myocardial ischemia /hypoxia; myocardium disorder; prognosis

The aim of this study to evaluate the prevalence and prognostic signicance of T-wave alternans in patients with severe CHF. We hypothesize that: (1) patients with T-wave alternans (regardless of the etiology of their heart failure) will have an increased cardiac mortality compared with patients who do not have T-wave alternans, and (2) T-wave alternans will be significantly more common in patients with severe CHF from an ischemic cardiomyopathy than in patients with severe CHF from a non-ischemic cardiomyopathy.

这项研究的目的是评估患病率和预后 重度充血性心力衰竭患者T波交替的意义。我们 假设：(1)T波交替的患者(无论 他们心力衰竭的病因学)将有更多的心脏 死亡率与没有T波交替的患者相比，以及 (2)T波交替在患有以下疾病的患者中更为常见 缺血性心肌病引起的严重心力衰竭比重症患者更严重 非缺血性心肌病所致的心力衰竭。