Disruption of the ability to simulate one’s personal future: insights from epilepsy and implications for neurosurgical planning and presurgical counselling

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The human memory system supports not only recollecting the past but also imagining the future (prospection). This is an important skill, enabling us to envision the consequences of alternative courses of action. Patients with temporal lobe epilepsy (TLE) frequently experience memory problems, suggesting that they will show parallel difficulties with prospection. We will study prospection in TLE patients before and after temporal lobe surgery, and the clinical implications thereof.