STUDIES OF METABOLIC BONE DISEASE

代谢性骨疾病的研究

• 批准号: 6274159
• 负责人: LOUIS V AVIOLI
• 金额: $ 2.24万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6274159
• 关键词: adolescence (12-20); adult human (21+); bone metabolism disorder; child (0-11); clinical research; disease /disorder classification; human subject; osteitis deformans; osteomalacia; osteoporosis; pathologic process; skeletal disorder

Adults and children with generalized skeletal abnormalities or abnormalities in mineral metabolism have been studied. Included were metabolic, radiographic, genetic and pathological studies to define the pathogenesis of a variety of disorders of bone and mineral metabolism, particularly osteoporosis, osteomalacia and Paget's disease. Several new disorders have been characterized.

患有全身性骨骼异常的成人和儿童 矿物质代谢的异常已经被研究过了。其中包括 代谢、放射学、遗传学和病理学研究，以确定 多种骨和矿物质代谢紊乱的发病机制， 尤其是骨质疏松症、骨软化症和佩吉特氏病。几个新的 疾病已经被描述为特征。