GENERAL CLINICAL RESEARCH CENTER

全科临床研究中心

• 批准号: 2716510
• 负责人: HAROLD J FALLON
• 金额: $ 212.12万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 1978
• 资助国家: 美国
• 起止时间: 1978-12-01 至 2002-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2716510
• 关键词: clinical research; human subject

The University of Alabama at Birmingham General Clinical Research Center is a multi-disciplinary facility available to faculty members of the Schools of Medicine and Dentistry for the pursuit of clinical investigation. The GCRC and its staff facilitate the meticulous control of experimental conditions, close observation and accurate monitoring of biologic phenomena, and the precise measurement of biochemical and physiological events which occur in patients and normal volunteers participating in research activities. In order to increase the efficiency and productivity of research efforts on individually funded projects, afford participants more flexibility in taking new research directions, and promoter more collaborative research among groups having multi- disciplinary approaches to science, we have negotiated construction of a new facility with University Hospital. This will include both inpatient and outpatient facilities as well as a processing laboratory and a Gene Therapy Core Laboratory in a discrete area on the ninth floor of the Medical Education Building, adjacent to the West Pavilion inpatient rooms. The Gene Therapy CORE will complement the UAB Gene Therapy/Vaccine Vector Core as well as address gene therapy needs for the present and anticipated future years. A separated suite of rooms which will house the CDMAS facility and offices for biostatisticians and coordinators will be located on the second floor of the same building directly below the GCRC unit and accessible via an elevator. In addition to the facilities listed above, this application includes a request for support for a Physiology and Metabolism Core Laboratory Facility, housed in the existing Energy Metabolism Research Unit in the Department of Nutrition Sciences. The proposed Physiology and Metabolism Core will provide access to expertise in the measurement and interpretation of physiological and provide access to expertise in the measurement and interpretation and of physiological and provide access to expertise in the measurement and interpretation of physiological and biochemical parameters essential conducting base clinical whole-body metabolic research for GCRC approved investigators. Changes in the GCRC facility will accommodate existing research activities as well as the perceived new emphasis on gene therapy.

阿拉巴马大学伯明翰综合临床研究中心 是一种多学科的设施，可供该学院的教职员工使用 医学和牙科学校追求临床 调查。政府资源中心及其职员协助审慎管制 实验条件，密切观察和准确监测 生物现象，以及生化和生物化学的精确测量 发生在患者和正常志愿者身上的生理事件 参与研究活动。为了提高工作效率 和个人资助项目的研究工作的生产力， 让参与者在选择新的研究方向时有更大的灵活性， 并促进具有多个 科学的学科方法，我们已经谈判建立了一个 与大学医院合作的新设施。这将包括两名住院患者 和门诊设施以及一个加工实验室和一个基因 治疗核心实验室位于九楼的一个独立区域 医学教育大楼，毗邻西馆住院室。 基因治疗核心将补充UAB基因治疗/疫苗载体 核心以及满足当前和预期的基因治疗需求 未来几年。一套独立的房间，将容纳CDMA 生物统计员和协调员的设施和办公室将设在 在同一座大楼的二楼，就在GCRC单位的正下方，并 可通过电梯到达。除了上面列出的设施外， 此应用程序包括对生理学和 新陈代谢核心实验室设施，安置在现有的能源中 营养科学系新陈代谢研究组。这个 拟议的生理学和新陈代谢核心将提供获得专业知识的途径 在测量和解释生理和提供通道 在测量和解释以及生理学方面的专业知识 并提供在测量和解释方面的专业知识 生理生化参数基本传导基础 GCRC批准的研究人员的临床全身代谢研究。 GCRC设施的变化将适应现有的研究活动 以及人们对基因治疗的新重视。