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TREATMENT OF CHILDREN WITH LOWER RISK LEUKEMIA INCORPORATING 6 THIOGUANINE

TREATMENT OF CHILDREN WITH LOWER RISK LEUKEMIA INCORPORATING 6 THIOGUANINE
使用 6 硫鸟嘌呤治疗低危白血病儿童
批准号：
6274646
负责人：
RAYMOND J HUTCHINSON
金额：
$2.15万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6274646
关键词：
6 thioguanine acute lymphocytic leukemia child (0-11) clinical research drug screening /evaluation human subject human therapy evaluation intravenous administration neoplasm /cancer chemotherapy oral administration pediatric neoplasm /cancer pediatric pharmacology pharmacokinetics

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中文摘要
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英文摘要
CCG-1942 is a pilot study of the efficacy of using 6-thioguanine (TG) in place of 6-mercaptopurine (MP) as one of the chemotherapy agents for the treatment of children with lower risk acute lymphoblastic leukemia (ALL). This pharmacokinetics of both oral and intravenous TG will be explored as a part of this research.
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