EVALUATION OF INTRA-ARTERIAL CISPLATIN IN TREATMENT OF BRAIN TUMORS

动脉内顺铂治疗脑肿瘤的评价

• 批准号: 6275026
• 负责人: STEVEN K GUDEMAN
• 金额: $ 1.58万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6275026
• 关键词: brain neoplasms; cis platinum compound; clinical research; clinical trials; drug screening /evaluation; glioma; human subject; human therapy evaluation; intraarterial administration; meningioma; metastasis; neoplasm /cancer chemotherapy; relapse /recurrence

The original study was a randomized one to evaluate new agents or techniques, including intraarterial chemotherapy, for the treatment of patients with recurrent gliomas. The randomized arms later were closed; treatment has continued with intraarterial cis-platin, since that mode of treatment had promising effects in some patients, in terms of clinical and radiographic improvement. The study was extended to patients with metastatic lesions and those with invasive skull tumors such as meningioma.

最初的研究是一项随机研究，旨在评估新药物或 技术，包括动脉化疗，用于治疗 复发性胶质瘤患者。 随后关闭随机化组; 治疗继续动脉内顺铂，因为该模式 在某些患者中， 临床和影像学改善。这项研究扩展到 转移性病变和侵袭性颅骨肿瘤患者 例如脑膜瘤。