Diversity and virulence determinants among 1000 clinical and environmental isolates of Burkholderia pseudomallei

1000 种鼻疽伯克霍尔德氏菌临床和环境分离株的多样性和毒力决定因素

• 批准号: nhmrc : 605820
• 负责人: A/Pr Philip Giffard
• 金额: $ 34.52万
• 依托单位: Menzies School of Health Research
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/diversity-virulence-determinants-burkholderia-pseudomallei/77350
• 关键词: Diversity; virulence; determinants; among; 1000

Melioidosis is an important infection in tropical northern Australia. It is a common cause of fatal pneumonia and blood infection in the region. Melioidosis results from infection with a soil bacterium. This project builds on the existing melioidosis collaboration between researchers in northern Australia and overseas to determine how the melioidosis bacterium can be so virulent and whether only a subset of the melioidosis bacteria found in the environment are capable of infecting humans.

类鼻疽是澳大利亚热带北方的一种重要传染病。它是该地区致命肺炎和血液感染的常见原因。类鼻疽是由土壤细菌感染引起的。该项目以澳大利亚北方和海外研究人员之间现有的类鼻疽合作为基础，以确定类鼻疽细菌为何如此致命，以及是否只有环境中发现的类鼻疽细菌的一个子集能够感染人类。