Surface coated nanodiamonds as drug delivery carriers and simultaneous imaging

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The design and development of next-generation nanocarriers as drug delivery platforms is an ongoing challenge in chemical and material sciences. Nanodiamonds are attractive candidates due to their biocompatibility, ease of functionalisation, and non-bleaching fluorescence. This project proposes an innovative approach to graft various polymer chains onto the surface of nanodiamonds to produce polymer-inorganic hybrid materials. This project will expand our knowledge of the influence of polymer chains on the stability of nanodiamonds and cellular uptake. The model drug gemcitabine and targeting bioactive ligands will also be conjugated onto the optimum produced hybrid materials for the drug delivery study.