HUMAN METHIONINE AND HOMOCYSTEINE METABOLISM

这个项目的主要目标是量化转甲基化的速率， 健康男性和健康男性的甲基化、硫化和半胱氨酸转化 没有证据表明维生素B6、B12或叶酸缺乏的妇女和 亚甲基四氢叶酸还原酶基因突变的特征 和胱硫氨酸合成酶，第二，确定是否 因此，蛋氨酸代谢确实存在明显的性别差异 绝经前同型半胱氨酸水平较低的原因 女人。在本报告所述期间，对五个主题进行了研究。全 很好地忍受了这些研究。 计划：继续招募志愿者。

The major goals of this project are to quantify rates of transmethylation, remethylation, transsulfuration, and cysteine turnover in healthy men and women without evidence of vitamin B6, B12 or folate deficiency and characterized for genetic mutations in methylenetetrahydrofolate reductase and cystathionine-synthase, and secondly, to determine whether or not apparent gender differences in methionine metabolism do exist thereby accounting for the reportedly lower homocysteine levels in premenopausal women. Five subjects were studied during the reporting period. All tolerated the studies well. Plan: To continue recruitment of volunteers.