CHOLESTEROL REDUCTION WITH LDL APHERESIS IN HYPERCHOLESTEROLEMIA

通过低密度脂蛋白血浆分离术降低高胆固醇血症中的胆固醇

• 批准号: 6278115
• 负责人: D ROGER ILLINGWORTH
• 金额: $ 2.86万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6278115
• 关键词: biomedical equipment safety; clinical biomedical equipment; clinical research; familial hyperlipoproteinemia type II; human subject; human therapy evaluation; hypercholesterolemia; low density lipoprotein; physical separation; plasmapheresis

Various techniques involving physical removal of plasma or selective removal of low density lipoproteins (LDL) have been used in the therapy of severe hypercholesterolemia. The present project aims to assess the efficacy and safety of the liposorber LA15, LDL adsorption column for the treatment of patients with severe heterozygous familial hyper- cholesterolemia.

涉及物理去除等离子体或选择性去除等离子体的各种技术。 低密度脂蛋白（LDL）的去除已经用于治疗 严重的高胆固醇血症 本项目旨在评估 脂质体LA 15、LDL吸附柱对低密度脂蛋白的有效性和安全性 治疗严重杂合子家族性高脂血症患者 胆固醇血症