膳食电解质摄入量、血管反应性和胰岛素抵抗-猫眼课题宝

膳食电解质摄入量、血管反应性和胰岛素抵抗

批准号：

6278158

负责人：

CYNTHIA L GABOURY

金额：

$2.86万

依托单位：

OREGON HEALTH & SCIENCE UNIVERSITY

依托单位国家：

美国

项目类别：

财政年份：

1997

资助国家：

美国

项目状态：

已结题

起止时间：

1997-12-01 至 1998-11-30

来源：

https://reporter.nih.gov/project-details/6278158

关键词：

blood pressure carbohydrate metabolism cardiovascular function clinical research dietary calcium dietary sodium electrolytes human subject hypertension insulin sensitivity /resistance nutrient intake activity nutrition related tag salt intake

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英文摘要

This proposal is intended to explore the association among salt sensitivity, disturbances of carbohydrate metabolism, and the dietary intake of electrolytes and minerals. Salt sensitive individuals and those with insulin resistance have similar abnormalities in cellular cation handling and abnormalities in vascular reactivity suggesting a pathophysiologic link. In salt sensitive hypertensive subjects the effects of adequate versus inadequate calcium intake on blood pressure, ex-vivo and in-vivo vascular function, and insulin resistance.

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