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GENETIC FACTORS IN OVARIAN CANCER AMOUNG ASHKENAZI JEWISH WOMEN

GENETIC FACTORS IN OVARIAN CANCER AMOUNG ASHKENAZI JEWISH WOMEN
德系犹太妇女卵巢癌的遗传因素
批准号：
6278351
负责人：
BETH Y. KARLAN
金额：
$3.92万
依托单位：
LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6278351
关键词：
Jewish brca gene clinical research family genetics female gene frequency gene mutation genetic counseling human subject neoplasm /cancer genetics oncogenes ovary neoplasms women's health

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英文摘要
Mutations in the BRCA1 gene have been identified to account for some of the inherited forms of breast cancer and ovarian cancer. In the Ashkenazi Jewish population, specific mutations appear to occur with increased prevalence. This study was undertaken to determine the frequency of the two most common BRCA1 mutations in Ashkenazi Jewish women with ovarian cancer.
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