EFFECTS OF ESTROGEN USE ON GH SECRETION AND BODY COMPOSITION MEASUREMENTS

雌激素的使用对 GH 分泌和身体成分测量的影响

• 批准号: 6279396
• 负责人: MICHAEL O THORNER
• 金额: $ 3.19万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6279396
• 关键词: adipose tissue; blood chemistry; body composition; computed axial tomography; estrogens; exercise; hormone biosynthesis; human subject; somatotropin

The purpose of this study is to determine the extent to which low dose oral contraceptives will affect spontaneous and stimulated (exercise) 24-hour GH secretions in young women. We will also examine the effect that estrogen has on body composition, specifically total body percent fat and regional distribution of body fat. Body composition will be determined using a 4 compartment model, regional fat distribution by CT and GH secretion by frequent blood sampling combined with ultrasensitive assay techniques. A total of 6 women have completed protocol and 5 have dropped out of study; will recruit 6 additional subjects.

本研究的目的是确定低剂量 口服避孕药会影响自发和刺激（运动） 24-小时GH分泌的年轻女性。 我们还将研究 雌激素对身体成分的影响，特别是对身体的百分比 脂肪和身体脂肪的区域分布。 身体成分将是 使用4房室模型确定，通过CT确定局部脂肪分布 和GH分泌的频繁采血结合 超灵敏测定技术。 共有6名妇女完成了 方案和5例退出研究;将再招募6例 科目