RECRUITMENT OF PERIPHERAL BLOOD HEMOPOIETIC PROGENITORS BY GCSF

该方案是题为“免疫治疗靶向”提案的一部分， 人乳腺癌细胞在体内的免疫增强和教育 自体树突细胞”。 长期目标是利用 在用于治疗乳腺癌的免疫疗法中，提出使用 人乳腺癌的动物模型来开发方法学。 这 免疫治疗将侧重于利用自体免疫的独特能力， 树突状细胞，有效的抗原呈递细胞，以增强宿主 乳腺癌的免疫监测。 本研究阶段 涉及从人外周血CD34+干细胞产生树突状细胞 并通过单采血液成分术收获它们。

This protocol is part of a proposal entitled "Immunotherapy targeting human breast cancer cells in vivo with immune-enhanced and educated autologous dendritic cells". With the long-term goal of utilizing immunotherapy for the treatment of breast cancer, it is proposed to use an animal model of human breast cancer to develop the methodology. This immunotherapy will focus on utilizing the unique capacity of autologous dendritic cells, potent antigen-presenting cells to enhance host immunosurveillance against breast cancer. This phase of the study involves generating dendritic cells from human peripheral CD34+ stem cells and harvesting them by means of apheresis.