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TUMOR NECROSIS FACTOR ALPHA AND KM POLYMORPHISMS IN GRAVES DISEASE

TUMOR NECROSIS FACTOR ALPHA AND KM POLYMORPHISMS IN GRAVES DISEASE
Graves 病中肿瘤坏死因子 α 和 KM 多态性
批准号：
6280088
负责人：
JANARDAN P PANDEY
金额：
$2.73万
依托单位：
MEDICAL UNIVERSITY OF SOUTH CAROLINA
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6280088
关键词：
Graves disease clinical research family genetics gene expression genetic disorder genetic mapping genetic polymorphism human subject tumor necrosis factor alpha

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英文摘要
The overall long-term goal of this investigation is to identify, map, and determine the mechanism of action of gene(s) responsible for susceptibility to Graves disease. Specific aims are to examine the role of candidate loci such as KM and TNFalpha in Graves diesease by case- control studies and to determine whether there is a major gene for Graves disease and if this gene is linked to any of the candidte loci by employing segregation and linkage analyses in families with Graves disease.
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