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GENETICS OF ATHEROSCLEROSIS IN MEXICAN AMERICANS

GENETICS OF ATHEROSCLEROSIS IN MEXICAN AMERICANS
墨西哥裔美国人动脉粥样硬化的遗传学
批准号：
6281021
负责人：
MICHAEL P STERN
金额：
$1.49万
依托单位：
UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6281021
关键词：
Mexican Americans atherosclerosis cardiovascular disorder epidemiology clinical research family genetics genetic mapping genetic polymorphism genetic susceptibility human subject noninsulin dependent diabetes mellitus obesity

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中文摘要
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英文摘要
This study is part of the San Antonio Family Heart Study, the first comprehensive genetic epidemiological study of atherosclerosis and its correlates in Mexican Americans. Its goal is to detect and map new polymorphic genes that influence variation in susceptibility to cardiovascular disease in Mexican Americans. Because non insulin dedepdent diabetes mellitus and obesity are risk factors for cardiovascular disease and are common in this population, the pleiotropic effects of diabetes and obesity-related genes on quantitative correlates of cardiovascular disease will also be study. More than 40 extended families will be studied and a complete risk factor profile will be developed.
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INSULIN SECRETION CAPACITY & INSULIN RESISTANCE IN SUBJECTS W/ VARIANT GENE
GENETICS OF ATHEROSCLEROSIS IN MEXICAN AMERICANS
INSULIN SECRETION CAPACITY & INSULIN RESISTANCE IN SUBJECTS W/ VARIANT GENE
CORE--FIELD AND CLINIC OPERATIONS
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