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BIOLOGICAL METAL CLUSTERS BIOPHYSICAL & MODEL STUDIES

BIOLOGICAL METAL CLUSTERS BIOPHYSICAL & MODEL STUDIES
生物金属簇 生物物理
批准号:
6120379
负责人:
MICHAEL J MARONEY
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-09-30 至 1999-08-31

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中文摘要
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英文摘要
We have also completed the first characterization of the active site of NiSOD from Streptomyces seoulensis. This study reveals that Ni site is bound to thiolate donors, like other Ni redox enzymes but unlike any previously characterized SOD. Examination of oxidized and reduced samples reveal a coordination number change (5 -> 4) and a shift in the edge energy appropriate for a one-electron process. There is also evidence that the active site consists of two Ni centers, one of which is not redox active in analogy with the CuZnSOD, and therefore must be composed of two subunits in the tetrameric enzyme.
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STRUCTURAL PARAMETERS INVOLVED IN METAL RECOGNITION
  • 批准号:
    8362356
  • 项目类别:
  • 资助金额:
    $0.19万
  • 财政年份:
    2011
  • 负责人:
    MICHAEL J MARONEY
  • 依托单位:
STRUCTURAL PARAMETERS INVOLVED IN METAL RECOGNITION
  • 批准号:
    8362081
  • 项目类别:
  • 资助金额:
    $0.14万
  • 财政年份:
    2011
  • 负责人:
    MICHAEL J MARONEY
  • 依托单位:
STRUCTURE AND FUNCTION OF UNIQUE NON-HEME IRON DIOXYGENASES
  • 批准号:
    8362326
  • 项目类别:
  • 资助金额:
    $0.22万
  • 财政年份:
    2011
  • 负责人:
    MICHAEL J MARONEY
  • 依托单位:
STRUCTURAL PARAMETERS INVOLVED IN METAL RECOGNITION
  • 批准号:
    8170361
  • 项目类别:
  • 资助金额:
    $0.03万
  • 财政年份:
    2010
  • 负责人:
    MICHAEL J MARONEY
  • 依托单位:
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