RENOVATION OF THE ULLMANN ANIMAL UNIT

乌尔曼动物单元的翻新

• 批准号: 2558178
• 负责人: Diane J. GAERTNER
• 金额: $ 59.89万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-05-18 至 2001-05-17
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2558178
• 关键词: animal care; animal colony; biomedical equipment purchase; biomedical resource; building /facility design /renovation

In this revised submission, matching funds are requested to renovate the Ullmann Animal Unit of the Albert Einstein College of Medicine, a major biomedical research institution with more than 44 million dollars in PHS funding. The Ullmann Animal Unit of 16,400 net square feet includes the 10th and 11th floors of the Ullmann building and house approximately half of AECOM's research animals, supporting more than 60 investigators and most major research programs of the college. The objective are (1) to convert largely unused dog rooms to additional barrier rodent space and more flexible space, (2) to improve the control of airflow and formite- borne rodent pathogens in rooms and hallways, (3) to improve cage sanitization, (4) to remove heat and humidity generated by cage washing, (5) to better vent exhaust anesthetic gasses, (6) to control temperature for Xenopus frogs, (7) to remove windows from animal rooms, and (8) to increase housing for pathogen-free mice. These objectives will be met by a 4-part renovation plan. In Part A, six large rooms will be renovated to create two barrier rodent suites and two multi-species rooms. The barrier rodent suites will be used to re-derive and re-stock the Ullman Building with pathogen-free rodents. The multi-species rooms will flexibly house small numbers of dogs, pigs, or sheep. In Part B, the cage-wash will be expanded to store dirty cages, the antiquated tunnel and rack washers will be replaced and the room exhaust will be upgraded. A new fume hood will be installed to vent waste anesthetic gasses from a heavily-used procedure room. In Part C, in-room supplemental cooling and new caging will be purchased to permit optimal housing and natural breeding of Xenopus frogs by providing temperatures under 72 degrees F. In Part D, 120 windows in 31 animals rooms on two floors will be eliminated to permit photoperiod control and to increase energy efficiency. This set of 4 related renovations will permit much-needed expansion of pathogen-free housing for rodents, including increasing numbers of immunodeficient, transgenic and knock-out mice in both the Ullman and Chanin buildings. These renovations are urgently needed and will assure compliance with the USDA Animal Welfare Act and DHHS policies related to room temperatures, controlling lighting and ventilation, working conditions for animal caretakers. The renovations will also assist us in maintaining our AAALAC accreditation.

在这份订正呈件中，要求提供配套资金， 阿尔伯特·爱因斯坦医学院的乌尔曼动物研究所， 生物医学研究机构，拥有超过4400万美元的PHS 经费乌尔曼动物单位16,400净平方英尺，包括 Ullmann大楼的10层和11层， AECOM的研究动物，支持60多名研究人员， 学院的主要研究项目。目标是（1） 将大部分闲置的狗房改造成额外的屏障啮齿动物空间， 更灵活的空间，（2）改善气流的控制， （3）改善笼舍 消毒，（4）除去洗笼产生的热量和湿气， (5)更好地排出麻醉气体，（6）控制温度 对于非洲爪蟾，（7）拆除动物房的窗户，以及（8） 增加了无病原体小鼠住房。这些目标将通过以下方式实现： 四个方面的改造计划。在A部分，六个大房间将被翻新， 建立两个屏障啮齿动物套房和两个多物种房间。阻挡 啮齿动物套房将用于重新衍生和重新储存厄尔曼大楼 没有病原体的啮齿动物多物种的房间将灵活的房子 少量的狗、猪或羊。在B部分，笼清洗将 扩大到存储脏笼子，过时的隧道和机架清洗机将 将被替换，房间排气将被升级。一个新的通风橱将 安装用于排出大量使用过程中产生的麻醉废气 房间在C部分，室内补充冷却和新的笼子将 购买是为了让非洲爪蟾蛙有最佳的栖息地和自然繁殖 通过提供低于72华氏度的温度。D部分，31个窗口中的120个窗口 两层楼的动物房将被取消，以允许光周期 控制和提高能源效率。这一套4相关 翻修将使急需的无病原体住房得以扩大， 啮齿类动物，包括越来越多的免疫缺陷，转基因和 乌尔曼和查宁大楼里的基因敲除小鼠这些翻新 迫切需要，并将确保符合美国农业部动物 福利法和卫生与公众服务部有关室温的政策， 照明和通风，动物管理员的工作条件。的 翻修也将有助于我们保持我们的AAALAC认证。