EXERCISE REHABILITATION OF YOUNGER AND OLDER CLAUDICANTS

年轻和老年跛行者的运动康复

• 批准号: 2653710
• 负责人: Andrew W Gardner
• 金额: $ 10.72万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-03-15 至 2000-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2653710
• 关键词: age difference; artery occlusion; claudication; exercise; gait; hemodynamics; human middle age (35-64); human old age (65+); human subject; leg; musculoskeletal circulation; pain; plethysmography; rehabilitation; statistics /biometry

The effects of age and exercise intensity of physical conditioning on claudication pain symptoms and leg circulation of patients with intermittent claudication will be examined. It is hypothesized that (1) older patients (greater than 70 years of age) will have greater disease severity, and greater relative improvements in claudication pain and leg circulation following 4 months of exercise rehabilitation than younger patients (greater than 60 years of age), and (2) the improvements of both age groups will be greater following a rehabilitation program that uses higher exercise intensity (70% of walking capacity) that a program that uses lower intensity (40% of walking capacity)> The clinical significance of these anticipated findings is the exercise rehabilitation becomes more effective in the treatment of claudication pain as patients age, and a program should consist of exercise at higher rather than lower intensity for greater improvements in claudication pain and leg circulation, which may circumvent disease progression to more serious endpoints.

年龄和运动强度对运动员体能训练的影响 患者的跛行疼痛症状和腿部循环 将检查间歇性跛行。 假设（1） 年龄较大的患者（大于70岁）将有更大的疾病 严重程度，以及跛行疼痛和腿部疼痛的相对改善 运动康复4个月后的循环比年轻 患者（大于60岁），（2）两者的改善 在使用康复计划后，年龄组将更大 更高的运动强度（步行能力的70%）， 使用较低强度（40%步行能力）>临床意义 这些预期的结果是运动康复变得更加 随着患者年龄的增长，有效治疗跛行疼痛， 该计划应包括更高而不是更低强度的锻炼 更好地改善跛行疼痛和腿部循环， 可以避免疾病进展到更严重的终点。

项目成果

Prediction of peak oxygen consumption in patients with intermittent claudication.

间歇性跛行患者的峰值耗氧量预测。

• DOI: 10.1177/000331979804900801
• 发表时间: 1998
• 期刊: Angiology
• 影响因子: 2.8
• 作者: Womack,CJ;Hyman,BA;Gardner,AW
• 通讯作者: Gardner,AW

Resting energy expenditure in patients with intermittent claudication and critical limb ischemia.

• DOI: 10.1016/j.jvs.2009.12.072
• 发表时间: 2010-06
• 期刊: JOURNAL OF VASCULAR SURGERY
• 影响因子: 4.3
• 作者: Gardner, Andrew W.;Montgomery, Polly S.
• 通讯作者: Montgomery, Polly S.

Fibrinolytic response to acute exercise in patients with peripheral arterial disease.

外周动脉疾病患者对急性运动的纤溶反应。

• DOI: 10.1097/00005768-200102000-00007
• 发表时间: 2001
• 期刊: Medicine and science in sports and exercise
• 影响因子: 4.1
• 作者: Womack,CJ;Ivey,FM;Gardner,AW;Macko,RF
• 通讯作者: Macko,RF

Lower extremity strength deficits in peripheral arterial occlusive disease patients with intermittent claudication.

外周动脉闭塞性疾病间歇性跛行患者的下肢力量缺陷。

• DOI: 10.1177/000331970105200102
• 发表时间: 2001
• 期刊: Angiology
• 影响因子: 2.8
• 作者: Scott-Okafor,HR;Silver,KK;Parker,J;Almy-Albert,T;Gardner,AW
• 通讯作者: Gardner,AW

Acute reduction in ankle/brachial index following smoking in chronic smokers with peripheral arterial occlusive disease.

患有外周动脉闭塞性疾病的慢性吸烟者吸烟后踝/臂指数急剧下降。

• DOI: 10.1177/000331979905000501
• 发表时间: 1999
• 期刊: Angiology
• 影响因子: 2.8
• 作者: Yataco,AR;Gardner,AW
• 通讯作者: Gardner,AW