HUMAN NEUTROPHIL PILOT STUDY

人类中性粒细胞试点研究

• 批准号: 6282716
• 负责人: RONALD E. WEINER
• 金额: $ 1.85万
• 依托单位: UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6282716
• 关键词: biological models; clinical research; diagnosis design /evaluation; human subject; lung injury; model design /development; neutrophil; respiratory disorder diagnosis

The overall objective of this proposal is to establish an in vitro model to measure lung leakiness using cultured endothelial cells. Endothelial cell blebbing and resultant lung leakiness is one of the earliest signs of lung injury. This type of model system will allow us to look at this phenomenon in vitro in a controlled environment.

这项建议的总体目标是建立一个体外模型 用培养的血管内皮细胞测量肺渗漏。内皮细胞 细胞起泡和由此导致的肺渗漏是最早的征兆之一。 肺损伤的症状。这种类型的模型系统将使我们能够看到 在受控环境中的体外现象。