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MICROSATELLITE DETECTION OF MALIGNANT CYTOLOGY

MICROSATELLITE DETECTION OF MALIGNANT CYTOLOGY
恶性细胞学的微卫星检测
批准号:
6282708
负责人:
Thiruchandurai Viswanathan Rajan
金额:
$1.85万
依托单位国家:
美国
项目类别:
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-12-01 至 1998-11-30

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中文摘要
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英文摘要
There have been some recent studies documenting the changes in microsatellite polymorphisms in malignant cells in comparison with normal cells obtained from the same patient. The specific aim of this proposal is to repeat these studies in our institution with two goals: 1) to confirm that microsatellite amplification can indeed detect differences in the genomes of (i) malignant cells in urine specimens and (ii) normal cells, such as lymphocytes, from the same patient; and 2) to refine the methodology such that early premalignant cells can also be detected.
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