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FEEDBACK CONTROL OF GROWTH HORMONE SECRETION

FEEDBACK CONTROL OF GROWTH HORMONE SECRETION
生长激素分泌的反馈控制
批准号：
6282593
负责人：
MICHAEL P WAJNRAJCH
金额：
$6.94万
依托单位：
WEILL MEDICAL COLL OF CORNELL UNIV
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-01-06 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6282593
关键词：
adolescence (12-20) biofeedback circadian rhythms clinical research gender difference hormone regulation /control mechanism human puberty human subject secretion somatotropin

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英文摘要
The Investigators continues to study the relationship between pubertal develop-ment and the secretion of and sensitivity to growth hormone. In adolescent boys and girls IGF-1 levels were found to be more dependent on sex hormone levels than on nocturnal growth hormone secretion. This difference was not dependent on puberty-related changes in the IGF binding proteins IGFBP-1, IGFBP-2, or IGFBP-3. This finding was presented at the Annual 1994 meeting of the Endocrine Society and is being prepared for publication. The Investigators continues to study the relationship between pubertal develop-ment and the secretion of and sensitivity to growth hormone. In adolescent boys and girls IGF-1 levels were found to be more dependent on sex hormone levels than on nocturnal growth hormone secretion. This difference was not dependent on puberty-related changes in the IGF binding proteins IGFBP-1, IGFBP-2, or IGFBP-3.
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Molecular Pathophysiology of Human Growth Disorders
Molecular Pathophysiology of Human Growth Disorders
FEEDBACK CONTROL OF GROWTH HORMONE SECRETION
ROLE OF GROWTH HORMONE RELEASING FACTOR IN SHORT STATURE
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