Does maladaptive remodelling of the heart and vasculature in response to preterm birth lead to long-term cardiovascular risk?

早产导致的心脏和脉管系统的适应不良重塑是否会导致长期心血管风险？

• 批准号: nhmrc : 1011354
• 负责人: A/Pr Graeme Polglase
• 金额: $ 35.68万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/does-maladaptive-remodelling-cardiovascular-risk/109578
• 关键词: Does; maladaptive; remodelling; heart; vasculature

Being born prematurely is linked to the development of high blood pressure (a major risk factor for cardiovascular disease) later in life. In this project we will examine whether injury to the cells lining the cardiovascular system and/or structural changes in the wall of the arteries and the heart, as a result of being born early, lead to an elevation in blood pressure and heart dysfunction in adulthood.

早产与以后患高血压（心血管疾病的主要危险因素）有关。在这个项目中，我们将研究过早出生是否会导致心血管系统细胞损伤和/或动脉和心脏壁的结构变化，从而导致成年后血压升高和心脏功能障碍。