COLLAGENASE IN THE TREATMENT OF DUPUYTREN'S DISEASE

胶原酶治疗掌腱膜挛缩症

• 批准号: 6123148
• 负责人: LAWRENCE C HURST
• 金额: $ 7.84万
• 依托单位: STATE UNIVERSITY NEW YORK STONY BROOK
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6123148
• 关键词: clinical research; collagenase; connective tissue; connective tissue disorder; connective tissue disorder chemotherapy; contracture; enzyme therapy; fingers; human subject; human therapy evaluation; limb movement

A Phase II random, placebo double blind trial of injectable collagenase is being studied as a non-operative treatment for Dupuytren's disease, a fixed flexion contracture deformity of the hand. This therapy may obviate the need for surgical fasciectomy for Dupuytren's disease.

一项II期随机、安慰剂双盲试验正在研究注射胶原酶作为Dupuytren病（一种手部固定屈曲挛缩畸形）的非手术治疗。 这种治疗方法可能会减少Dupuytren病的手术筋膜切除术的需要。