STUDY OF THE RELATIVE SAFETY AND EFFICACY OF COLLAGENASE THERAPY

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。这项研究的目的是测试一种名为胶原酶的实验性药物是否会溶解和破裂因杜普伊特伦病而导致手指痉挛的组织(S)。如果你的手指在三次随机注射后对注射没有反应，或者如果你在三次随机注射后仍有其他手指受到Dupuytren病的影响，你有资格参加延长阶段的研究。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of the study is to test whether an experimental drug called collagenase will dissolve and rupture the tissue causing the contracture of your finger(s)due to your Dupuytren's disease. If your finger has failed to respond to injection after three random injections, or if you still have other fingers affected by Dupuytren's disease after three random injections, you are eligible to participate in an extended phase of the study.