UCC--RCRII CENTER

关于建立一个临床研究中心的建议， 创建基础设施，以有效地促进临床研究 UCC，提出了一种新的基于UCC的。描述了三个不同的组件：核心 设施、教师发展计划和临床研究优先事项 区域。 核心设施将有足够的空间进行临床 研究。它还将有计算机设施，用于数据输入和 统计分析。支持人员，如 流行病学家、统计学家、护士、数据录入规范、研究技术人员 而秘书，开展临床研究所需的也是 包括在内。教师发展部分旨在增加 通过招聘提高机构的临床研究能力 一位有成就的临床研究人员和目前的能力 现有教职员工。临床研究开发将优先考虑的领域 需要强调的是描述了。这些都是在目前的基础上选择的 研究兴趣、能力和患者可获得性。四名飞行员 项目随本申请一起提交。在卫生保健中 提交了评估和交付优先领域两个项目。一个 老年人健康预防支持性模式旨在改善 老年患者的生活质量和健康结局。第二 该项目旨在建立一个社会、流行病学和医学登记册 波多黎各一个直辖市明确界定的人口数据 里科。在慢性病优先领域，提交了一个项目。它 目的研究波多黎各的临床和免疫遗传学特征。 患有系统性红斑狼疮的Rican患者。最后，审判是为了 评价HIV-1感染性疾病的免疫学和病毒学标志物 西班牙裔人口的进步是提交的。这场审判是 慢性病优先领域。 一种积极推动 临床研究，关注研究对象的权利 并对科学完整性进行了描述。行政架构 由一名私人助理、私人助理和几个委员会组成，负责监督 该计划的发展和运作。

A proposal for the establishment of a clinical research center that creates an infrastructure to effectively promote clinical research at UCC, is presented. Three distinct components are described: a core facility, a faculty development program and clinical research priority areas. The core facility will have adequate space for the conduct of clinical research. It will also have computer facilities for data entry and statistical analysis. Support personnel such as an epidemiologist,statistician,nurses,data entry spec., research technicians and secretary, necessary to carry out clinical research are also included. The faculty development component is designed to increase the clinical research capability of the institution through the recruitment of an accomplished clinical researcher and capacitation of presently existing faculty. Priority areas where clinical research development will be emphasized are described. These were chosen on the basis of present research interests, capabilities and patient availability. Four pilot projects are submitted with this application. In the Health Care Evaluation and Delivery priority area two projects are submitted. A supportive model for health prevention in the elderly aims to improve the quality of life and health outcomes of geriatric patients. The second project aims to create a registry of social, epidemiological and medical data of a well defined population in one of the municipalities of Puerto Rico. In the Chronic Diseases priority area one project is submitted. It aims to study the clinical and immunogenetic characteristics of Puerto Rican patients with systemic lupus erythematosus. Finally, a trial to evaluate immunological and virological markers of HIV-1 infection disease progression in a Hispanic population is submitted. This trial is part of the Chronic Diseases priority area. An administrative structure that will actively promote development of clinical research, be watchful of the rights of human subjects studied and of scientific integrity is described. The administrative structure is composed of a PI, PD and several committees that oversee the development and functioning of the Program.