SIMPLIFIED LOW IODINE DIET FOR I 131 RADIOIODINE DIAGNOSTIC IMAGING

I 131 放射性碘诊断成像的简化低碘饮食

• 批准号: 6264101
• 负责人: STEPHANIE L LEE
• 金额: $ 4.27万
• 依托单位: TUFTS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6264101
• 关键词: bioimaging /biomedical imaging; clinical research; clinical trial phase I; comorbidity; dietary restriction; dietary trace element; human subject; human therapy evaluation; hyperthyroidism; iodine; metastasis; neoplasm /cancer radionuclide diagnosis; nutrition related tag; radionuclide imaging /scanning; radionuclide therapy; thyroid neoplasm

Radioactive iodine is used for the diagnosis of distant and local metastases of thyroid cancer and therapy of thyrotoxicosis and thyroid cancer. Because of the high iodine content of the American diet, the efficacy of radioiodine is diminished unless that patient is placed on a strict low iodine diet. This diet which consists of freshly prepared meals and homemade breads and pastas is nearly impossible to follow with the American dietary habits of eating in restaurants and using convenience foods. After review of the iodine content of currently available foods, the objective of this study is to develop and test a convenient and palatable out-patient diet to decrease iodine intake and excretion to less than 50mcg/24hrs in normal volunteers and patients undergoing routine radioactive iodine diagnostic scanning or therapy for thyrotoxicosis and thyroid cancer.

放射性碘用于诊断甲状腺癌的远处和局部转移，治疗甲状腺毒症和甲状腺癌。由于美国人的饮食中碘含量很高，除非严格的低碘饮食，否则放射性碘的疗效就会降低。这种由新鲜准备的食物、自制面包和意大利面组成的饮食几乎不可能遵循美国人在餐馆吃饭和使用方便食品的饮食习惯。在回顾了现有食物的碘含量后，本研究的目的是开发和测试一种方便和可口的门诊饮食，以将正常志愿者和接受甲状腺毒症和甲状腺癌常规放射性碘诊断扫描或治疗的患者的碘摄入量和排泄量减少到50mcg/24小时以下。