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ORALLY ADMINISTERED SP 303 FOR TREATMENT OF DIARRHEA IN AIDS PATIENTS

ORALLY ADMINISTERED SP 303 FOR TREATMENT OF DIARRHEA IN AIDS PATIENTS
口服 SP 303 用于治疗艾滋病患者的腹泻
批准号：
6304511
负责人：
Paul R Skolnik
金额：
$4.27万
依托单位：
TUFTS MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
项目状态：
已结题
起止时间：
1999-12-01 至 2001-02-28
来源：
https://reporter.nih.gov/project-details/6304511
关键词：
AIDS therapy HIV infections antiAIDS agent clinical research combination chemotherapy comorbidity diarrhea drug adverse effect drug resistance drug screening /evaluation gene mutation human subject human therapy evaluation oral administration therapy compliance virus load

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中文摘要
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英文摘要
Diarrhea is a substantial problem for many HIV-infected persons. The causes of diarrhea in this patient group are many; they include problems with absorption, infections that may cause diarrhea, and side effects of drug that are needed to treat HIV infection or prevent opportunistic illnesses. Methods of decreasing drugs side effects are especially important now that highly active antiretroviral therapy is available that decreases viral load and increases survival. Taking these drugs without interruption is important to decrease the chances of mutations in the HIV genome that might result in drug resistance. SP-303 is an investigational agent that has been effective in decreasing diarrhea in other patient groups. This study will determine the safety and efficacy of this drug for the treatment of diarrhea in patients with AIDS.
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    $0.22万
  • 财政年份：
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