SOCA: LONGITUDINAL STUDY OF OCULAR COMPLICATIONS OF AIDS

SOCA：艾滋病眼部并发症的纵向研究

• 批准号: 6305853
• 负责人: DOROTHY Nahm FRIEDBERG
• 金额: $ 2.1万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-12-01 至 2000-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6305853
• 关键词: AIDS; HIV infections; clinical research; cytomegalovirus retinitis; epidemiology; human subject; longitudinal human study; medical complication; opportunistic infections; pathologic process; quality of life

The objectives of this NIH-funded prospective, observational, longitudinal study is to provide information on the incidence and course of ocular complications of AIDS in the face of changing anti-HIV and anti-CMV therapies. The study will monitor secular trends in the incidence of CMV retinitis and other ocular complication of AIDS; will determine the effect of HAART-induced changes in immune status on the risk of CMV retinitis and other ocular complications of AIDS; will determine the characteristics of populations at high risk; and will evaluate the effects of treatments on visual function, QOL, and survival.

这项由美国国立卫生研究院资助的前瞻性、观察性、纵向研究的目的是提供关于艾滋病眼部并发症的发病率和病程的信息，以应对不断变化的抗HIV和抗CMV治疗。该研究将监测CMV视网膜炎和其他AIDS眼部并发症发病率的长期趋势;将确定HAART诱导的免疫状态变化对CMV视网膜炎和其他AIDS眼部并发症风险的影响;将确定高危人群的特征;并将评估治疗对视觉功能、QOL和生存率的影响。