SOCA: LONGITUDINAL STUDY OF THE OCULAR COMPLICATIONS OF AIDS

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。这项由美国国立卫生研究院资助的前瞻性、观察性、纵向研究的目的是提供关于艾滋病眼部并发症的发病率和病程的信息，以应对不断变化的抗HIV和抗CMV治疗。该研究将监测CMV视网膜炎和其他AIDS眼部并发症发病率的长期趋势;将确定HAART诱导的免疫状态变化对CMV视网膜炎和其他AIDS眼部并发症风险的影响;将确定高危人群的特征;并将评估治疗对视觉功能、QOL和生存率的影响。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objectives of this NIH-funded prospective, observational, longitudinal study is to provide information on the incidence and course of ocular complications of AIDS in the face of changing anti-HIV and anti-CMV therapies. The study will monitor secular trends in the incidence of CMV retinitis and other ocular complication of AIDS; will determine the effect of HAART-induced changes in immune status on the risk of CMV retinitis and other ocular complications of AIDS; will determine the characteristics of populations at high risk; and will evaluate the effects of treatments on visual function, QOL, and survival.