HPA AXIS FUNCTION AND HIPPOCAMPUS IN WOMEN WITH SEXUAL ABUSE RELATED PTSD
HPA AXIS FUNCTION AND HIPPOCAMPUS IN WOMEN WITH SEXUAL ABUSE RELATED PTSD
批准号:
6306194
负责人:
James Douglas Bremner
金额:
$3.45万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1999
资助国家:
美国
项目状态:
已结题
起止时间:
1999-12-01 至 2000-11-30
中文摘要
本研究的目的是测量儿童期性虐待相关创伤后应激障碍(PTSH)女性下丘脑-垂体-肾上腺轴(HPA)功能和海马的变化。这项研究将包括用MRI测量海马体积,用神经心理学测试评估记忆功能,24小时血浆皮质醇、ACTH和β -内啡肽的测量,CRF和ACTH刺激试验,以及用地塞米松测量记忆功能。
英文摘要
The purpose of this study is to measure the hypothalamic-pituitary-adrenal axis (HPA) function and the hippocampus in women with Posttraumatic Stress Disorder (PTSH) related to childhood sexual abuse. The study will entail measurement of hippocampal volume with MRI, assessment of memory function with neuropsychological testing, 24 hour measurement of plasma cortisol, ACTH and Beta-endorphin, a CRF and ACTH challenge test and administration of dexamethasone with measurement of memory function.
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会议论文
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Dopamine function, inflammation and connectivity in PTSD
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批准号:10405521
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Dopamine function, inflammation and connectivity in PTSD
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批准号:9973958
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资助金额:$76.88万
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财政年份:2020
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批准号:10718694
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资助金额:$0.0万
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依托单位:
A Multisite Randomized Controlled Trial of Mindfulness Meditation Therapy for PTS
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资助金额:$0.0万
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财政年份:2012
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Imaging Core
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批准号:7931301
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Mechanisms of Depression in CVD
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依托单位:
Mechanisms of Depression in CVD
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Mechanisms of Depression in CVD
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Mechanisms of Depression in CVD
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财政年份:2008
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Benzodiazepine Receptor in PTSD
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Biological Correlates of Traumatic Stress
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财政年份:2006
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Biological Correlates of Traumatic Stress
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海外基金