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ALOPECIA AREATA REGISTRY

ALOPECIA AREATA REGISTRY
斑秃登记处
批准号:
6358789
负责人:
MADELEINE DUVIC
金额:
$58.39万
依托单位国家:
美国
项目类别:
财政年份:
2000
资助国家:
美国
项目状态:
已结题
起止时间:
2000-09-28 至 2005-09-29

项目摘要

项目成果

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中文摘要
翻译
斑秃是一种相当常见的疾病,其中头发从部分头皮,全部头皮或整个身体脱落。在某些情况下,这种疾病是遗传性的。它被认为是一种自身免疫性疾病。斑秃登记处将收集具有临床特征的三种斑秃患者,斑秃(头皮毛发斑驳脱落),全身性脱发(头皮毛发全部脱落)和全身性脱发(全身毛发完全脱落)。这将是多代家庭和同胞对对照患者的集合。这些具有良好特征的患者将被用于在人类基因组中搜索与疾病相关的基因座和/或基因,并且将建立一种机制,使对这种疾病的病理生理学或治疗研究感兴趣的研究人员能够与患有适当形式的疾病的患者进行接触,以进行相关研究。
英文摘要
Alopecia Areata is a fairly common disease in which hair is lost either from part of the scalp, all of the scalp or the entire body. In some cases the disease is hereditary. It is thought to be an autoimmune disease. The Alopecia Areata Registry will collect clinically well characterized patients with these three forms of Alopecia Areata, alopecia areata (patchy loss of the scalp hair), alopecia totalis (total loss of all scalp hair) and alopecia universalis (complete loss of all hair everywhere on the body). This will be a collection of patients both in multi generational families and in sib pairs with controls. These well characterized patients will be used to search the human genome for disease associated loci and/or genes and a mechanism will be put in place to allow researchers interested in doing pathophysiology or treatment studies of this disease to be put in contact with patients having the appropriate form of the disease for the studies in question.
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